STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OI25_7700[M] COG0768 Cell division protein FtsI/penicillin-binding protein 2. (284 aa)    
Predicted Functional Partners:
ftsW
Cell division protein FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily.
 
 
 0.922
ftsI-2
Penicillin binding transpeptidase domain protein; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily.
  
  
 
0.917
ftsI
Penicillin binding transpeptidase domain protein; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.
  
  
 
0.910
mrdB
Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.
 
 
 0.897
murE
UDP-N-acetylmuramyl-tripeptide synthetase family protein; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily.
 
  
 0.839
ftsQ
Cell division FtsQ family protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.
 
 
 0.806
ddl
D-alanine--D-alanine ligase family protein; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family.
 
 
 0.756
murC
UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family.
 
 
 0.746
murD
UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.
 
  
 0.692
murF
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase family protein; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.
 
  
 0.661
Your Current Organism:
Paraburkholderia fungorum
NCBI taxonomy Id: 134537
Other names: ATCC BAA-463, Burkholderia fungorum, Burkholderia fungorum Coenye et al. 2001, Burkholderia sp. LMG 16225, Burkholderia sp. LMG 16307, Burkholderia sp. LMG16225, Burkholderia sp. LMG16307, CCUG 31961, CIP 107096, DSM 17061, JCM 21562, LMG 16225, LMG:16225, NBRC 102489, P. fungorum, Paraburkholderia fungorum (Coenye et al. 2001) Sawana et al. 2015, strain Croize P763-2
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