STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
asp3Accessory Sec system protein Asp3; Derived by automated computational analysis using gene prediction method: Protein Homology. (178 aa)    
Predicted Functional Partners:
asp1
Accessory Sec system protein Asp1; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 
 0.997
asp2
Accessory Sec system protein Asp2; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 
 0.996
gtfB
Accessory Sec system glycosylation chaperone GtfB; Required for polymorphic O-glycosylation of the serine-rich repeat protein in this bacteria. A stabilizing protein that is part of the accessory SecA2/SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. The GtfA-GtfB complex adds GlcNAc from UDP-GlcNAc to the substrate protein, attaching the first sugar residue. Stabilizes the glycosylation activity of GtfA. Has no N-acetylglucosaminyl transferase activity on its own.
 
 
 
 0.977
gtfA
Accessory Sec system glycosyltransferase GtfA; Required for polymorphic O-glycosylation of the serine-rich repeat protein in this bacteria. Catalyzes the first step in glycosylation by transferring N-acetylglucosamine from UDP-GlcNAc to serine residues in the substrate protein. Part of the accessory SecA2/SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon.
 
 
 
 0.974
APD31346.1
Nucleotide sugar synthetase-like protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 
 0.926
secY2
Accessory Sec system protein translocase subunit SecY2; Part of the accessory SecA2/SecY2 system specifically required for export of possible cell wall proteins. The central subunit of a protein translocation channel.
 
   
 0.849
APD31317.1
Alpha/beta hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.793
secA2
Accessory Sec system translocase SecA2; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
 
   
 0.785
APD31347.1
Glycosyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 
 0.705
APD31123.1
Adhesin; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.704
Your Current Organism:
Streptococcus iniae
NCBI taxonomy Id: 1346
Other names: ATCC 29178, CCUG 27303, CIP 102508, DSM 20576, LMG 14520, LMG:14520, S. iniae, Streptococcus shiloi, strain PW
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