STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
APD31511.1Class 1b ribonucleoside-diphosphate reductase subunit beta; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. (319 aa)    
Predicted Functional Partners:
APD31512.1
Ribonucleotide-diphosphate reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
 
 0.999
APD31215.1
Ribonucleotide reductase assembly protein NrdI; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NrdI family.
 
 0.997
APD31513.1
NrdH-redoxin; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.864
cmk
Cytidylate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.819
APD31658.1
Nucleoside-diphosphate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.792
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
     
 0.775
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
     
 0.766
tmk
dTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
  
 
 0.653
fabF
Beta-ketoacyl-[acyl-carrier-protein] synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
   
 
 0.606
APD31782.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.601
Your Current Organism:
Streptococcus iniae
NCBI taxonomy Id: 1346
Other names: ATCC 29178, CCUG 27303, CIP 102508, DSM 20576, LMG 14520, LMG:14520, S. iniae, Streptococcus shiloi, strain PW
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.