| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KXA11964.1 | KXA12533.1 | HMPREF3206_01840 | HMPREF3206_01721 | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family; KEGG: fnu:FN0213 3.9e-47 N-acylneuraminate-9-phosphatase K03270; Psort location: Cytoplasmic, score: 9.97. | Sugar isomerase, KpsF/GutQ family; KEGG: fnu:FN0903 6.1e-106 polysialic acid capsule expression protein kpsF; K06041 arabinose-5-phosphate isomerase; Psort location: Cytoplasmic, score: 8.96; Belongs to the SIS family. GutQ/KpsF subfamily. | 0.971 |
| KXA11964.1 | KXA14370.1 | HMPREF3206_01840 | HMPREF3206_01055 | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family; KEGG: fnu:FN0213 3.9e-47 N-acylneuraminate-9-phosphatase K03270; Psort location: Cytoplasmic, score: 9.97. | Putative 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.704 |
| KXA11964.1 | kdsA | HMPREF3206_01840 | HMPREF3206_00731 | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family; KEGG: fnu:FN0213 3.9e-47 N-acylneuraminate-9-phosphatase K03270; Psort location: Cytoplasmic, score: 9.97. | 3-deoxy-8-phosphooctulonate synthase; KEGG: fnu:FN1224 2.9e-122 2-dehydro-3-deoxyphosphooctonate aldolase K01627; Psort location: Cytoplasmic, score: 9.97; Belongs to the KdsA family. | 0.958 |
| KXA11964.1 | kdsB | HMPREF3206_01840 | HMPREF3206_00191 | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family; KEGG: fnu:FN0213 3.9e-47 N-acylneuraminate-9-phosphatase K03270; Psort location: Cytoplasmic, score: 9.97. | 3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.945 |
| KXA12533.1 | KXA11964.1 | HMPREF3206_01721 | HMPREF3206_01840 | Sugar isomerase, KpsF/GutQ family; KEGG: fnu:FN0903 6.1e-106 polysialic acid capsule expression protein kpsF; K06041 arabinose-5-phosphate isomerase; Psort location: Cytoplasmic, score: 8.96; Belongs to the SIS family. GutQ/KpsF subfamily. | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family; KEGG: fnu:FN0213 3.9e-47 N-acylneuraminate-9-phosphatase K03270; Psort location: Cytoplasmic, score: 9.97. | 0.971 |
| KXA12533.1 | KXA14370.1 | HMPREF3206_01721 | HMPREF3206_01055 | Sugar isomerase, KpsF/GutQ family; KEGG: fnu:FN0903 6.1e-106 polysialic acid capsule expression protein kpsF; K06041 arabinose-5-phosphate isomerase; Psort location: Cytoplasmic, score: 8.96; Belongs to the SIS family. GutQ/KpsF subfamily. | Putative 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.824 |
| KXA12533.1 | KXA16507.1 | HMPREF3206_01721 | HMPREF3206_00275 | Sugar isomerase, KpsF/GutQ family; KEGG: fnu:FN0903 6.1e-106 polysialic acid capsule expression protein kpsF; K06041 arabinose-5-phosphate isomerase; Psort location: Cytoplasmic, score: 8.96; Belongs to the SIS family. GutQ/KpsF subfamily. | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.827 |
| KXA12533.1 | kdsA | HMPREF3206_01721 | HMPREF3206_00731 | Sugar isomerase, KpsF/GutQ family; KEGG: fnu:FN0903 6.1e-106 polysialic acid capsule expression protein kpsF; K06041 arabinose-5-phosphate isomerase; Psort location: Cytoplasmic, score: 8.96; Belongs to the SIS family. GutQ/KpsF subfamily. | 3-deoxy-8-phosphooctulonate synthase; KEGG: fnu:FN1224 2.9e-122 2-dehydro-3-deoxyphosphooctonate aldolase K01627; Psort location: Cytoplasmic, score: 9.97; Belongs to the KdsA family. | 0.987 |
| KXA12533.1 | kdsB | HMPREF3206_01721 | HMPREF3206_00191 | Sugar isomerase, KpsF/GutQ family; KEGG: fnu:FN0903 6.1e-106 polysialic acid capsule expression protein kpsF; K06041 arabinose-5-phosphate isomerase; Psort location: Cytoplasmic, score: 8.96; Belongs to the SIS family. GutQ/KpsF subfamily. | 3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.884 |
| KXA12533.1 | lpxA | HMPREF3206_01721 | HMPREF3206_00273 | Sugar isomerase, KpsF/GutQ family; KEGG: fnu:FN0903 6.1e-106 polysialic acid capsule expression protein kpsF; K06041 arabinose-5-phosphate isomerase; Psort location: Cytoplasmic, score: 8.96; Belongs to the SIS family. GutQ/KpsF subfamily. | acyl-[acyl-carrier-protein]-UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.798 |
| KXA12533.1 | lpxC | HMPREF3206_01721 | HMPREF3206_00271 | Sugar isomerase, KpsF/GutQ family; KEGG: fnu:FN0903 6.1e-106 polysialic acid capsule expression protein kpsF; K06041 arabinose-5-phosphate isomerase; Psort location: Cytoplasmic, score: 8.96; Belongs to the SIS family. GutQ/KpsF subfamily. | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | 0.777 |
| KXA12533.1 | lpxD | HMPREF3206_01721 | HMPREF3206_01767 | Sugar isomerase, KpsF/GutQ family; KEGG: fnu:FN0903 6.1e-106 polysialic acid capsule expression protein kpsF; K06041 arabinose-5-phosphate isomerase; Psort location: Cytoplasmic, score: 8.96; Belongs to the SIS family. GutQ/KpsF subfamily. | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.760 |
| KXA12533.1 | lpxK | HMPREF3206_01721 | HMPREF3206_01402 | Sugar isomerase, KpsF/GutQ family; KEGG: fnu:FN0903 6.1e-106 polysialic acid capsule expression protein kpsF; K06041 arabinose-5-phosphate isomerase; Psort location: Cytoplasmic, score: 8.96; Belongs to the SIS family. GutQ/KpsF subfamily. | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.853 |
| KXA14370.1 | KXA11964.1 | HMPREF3206_01055 | HMPREF3206_01840 | Putative 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family; KEGG: fnu:FN0213 3.9e-47 N-acylneuraminate-9-phosphatase K03270; Psort location: Cytoplasmic, score: 9.97. | 0.704 |
| KXA14370.1 | KXA12533.1 | HMPREF3206_01055 | HMPREF3206_01721 | Putative 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | Sugar isomerase, KpsF/GutQ family; KEGG: fnu:FN0903 6.1e-106 polysialic acid capsule expression protein kpsF; K06041 arabinose-5-phosphate isomerase; Psort location: Cytoplasmic, score: 8.96; Belongs to the SIS family. GutQ/KpsF subfamily. | 0.824 |
| KXA14370.1 | KXA16507.1 | HMPREF3206_01055 | HMPREF3206_00275 | Putative 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.837 |
| KXA14370.1 | kdsA | HMPREF3206_01055 | HMPREF3206_00731 | Putative 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 3-deoxy-8-phosphooctulonate synthase; KEGG: fnu:FN1224 2.9e-122 2-dehydro-3-deoxyphosphooctonate aldolase K01627; Psort location: Cytoplasmic, score: 9.97; Belongs to the KdsA family. | 0.821 |
| KXA14370.1 | kdsB | HMPREF3206_01055 | HMPREF3206_00191 | Putative 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.966 |
| KXA14370.1 | lpxA | HMPREF3206_01055 | HMPREF3206_00273 | Putative 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | acyl-[acyl-carrier-protein]-UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.830 |
| KXA14370.1 | lpxC | HMPREF3206_01055 | HMPREF3206_00271 | Putative 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | 0.833 |