Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_1000Cysteine synthase. (330 aa)    
Predicted Functional Partners:
ACPL_4122
Cysteine synthase.
  
  
 
0.914
ACPL_7742
Hypothetical protein; Acetyltransferase (isoleucine patch superfamily).
  
 0.826
metB
Cystathionine beta-lyases/cystathionine gamma-synthases.
 
 
 0.796
megL
Methionine-gamma-lyase; Cystathionine beta-lyases/cystathionine gamma-synthases.
 
 
 0.794
cysA
Cystathionine beta-lyases/cystathionine gamma-synthases.
 
 
 0.782
ocd
Predicted ornithine cyclodeaminase, mu-crystallin homolog.
  
  
 0.747
argF-4
Ornithine carbamoyltransferase.
     
 0.729
ACPL_998
Hypothetical protein.
       0.709
sat1
Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate.
  
  
 0.698
ACPL_1002
Hypothetical protein.
   
 
 0.693
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
Server load: low (32%) [HD]