STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
megLMethionine-gamma-lyase; Cystathionine beta-lyases/cystathionine gamma-synthases. (387 aa)    
Predicted Functional Partners:
cysM-2
Cystathionine beta-synthase; Cysteine synthase.
 
 0.994
ACPL_952
Cystathionine beta-synthase; Cysteine synthase.
 
 0.994
metH
5-methyltetrahydrofolate-homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 
 0.980
ACPL_364
Aminotransferase; Aspartate/tyrosine/aromatic aminotransferase.
 
 
 0.952
nirA
Sulfite reductase, beta subunit (hemoprotein); Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
  
 0.947
fdhF
Molybdopterin oxidoreductase; Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
  
 0.937
ilvE
Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase.
  
 0.928
sahH
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
  
 0.926
cysA
Cystathionine beta-lyases/cystathionine gamma-synthases.
  
  
 
0.921
metB
Cystathionine beta-lyases/cystathionine gamma-synthases.
  
  
 
0.911
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.