Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
fbiALPPG:FO 2-phospho-L-lactate transferase. (316 aa)    
Predicted Functional Partners:
ACPL_1047
Gamma-glutamyl ligase.
 
 
 0.999
fbiD
Hypothetical protein; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor.
 
  
 0.991
fbiC
FO synthase; Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes.
 
  
 0.989
ACPL_1851
Hypothetical protein; Displays ATPase and GTPase activities.
  
  
 0.838
ACPL_1046
Putative 45.4 kDa protein in thiaminase I 5'region; NTP pyrophosphohydrolases including oxidative damage repair enzymes.
  
    0.823
ACPL_4576
Putative F420-dependent oxidoreductase; Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases.
 
   
 0.785
ACPL_2601
Putative dehydrogenase; Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases.
 
   
 0.771
ACPL_6718
Uncharacterized protein.
 
   
 0.768
ACPL_5270
Alkanesulfonate monooxygenase; Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases.
 
   
 0.758
ACPL_2949
Uncharacterized protein.
 
   
 0.754
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.