Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
nfiDeoxyribonuclease V; DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. (215 aa)    
Predicted Functional Partners:
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
  
    0.589
ACPL_1057
Putative 47.3 kDa protein in thcA 5'region; Transcriptional activator of acetoin/glycerol metabolism.
       0.562
manB
Phosphomannomutase.
       0.552
ACPL_1060
Tetraacyldisaccharide 4'-kinase; Belongs to the UPF0434 family.
       0.497
ACPL_1055
Uncharacterized protein conserved in bacteria.
       0.488
ald1
NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family.
       0.488
ACPL_1061
Glucosamine 6-phosphate synthetase; Contains amidotransferase and phosphosugar isomerase domains.
       0.464
ACPL_1062
Zinc transporter 9; Co/Zn/Cd efflux system component.
       0.452
mpi
Phosphomannose isomerase.
       0.422
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.