STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mtrBTwo-component system, OmpR family, sensor histidine kinase MtrB; Signal transduction histidine kinase. (532 aa)    
Predicted Functional Partners:
ACPL_1066
Transcriptional regulatory protein yycF; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
 
 0.996
ACPL_3425
Phosphate regulon transcriptional regulatory protein phoB; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
  
  0.942
ACPL_6800
yclJ-like uncharacterized transcriptional regulatory protein; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
  
 0.932
ACPL_1068
Lipoprotein lpqB.
 
    0.921
barA
Sensory box histidine kinase/response regulator; Signal transduction histidine kinase.
 
 
0.904
ACPL_4809
Two-component system sensor protein; Signal transduction histidine kinase.
 
 
0.872
ACPL_1069
Hypothetical protein; Predicted amidophosphoribosyltransferases.
  
    0.856
ACPL_4801
Signal transduction histidine kinase.
 
0.832
ACPL_2319
Putative transcriptional regulator ycf27; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
 
 
 0.784
phoR
Sensory box histidine kinase PhoR; Signal transduction histidine kinase.
 
 
0.746
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.