Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ftsEMethionine import ATP-binding protein metN; Part of the ABC transporter FtsEX involved in cellular division. (226 aa)    
Predicted Functional Partners:
ACPL_1080
Macrolide export ATP-binding/permease protein macB; Part of the ABC transporter FtsEX involved in cellular division; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
 
 0.998
ACPL_5899
Cell division protein.
  
 0.985
ACPL_4938
Cell division protein.
  
 0.972
ACPL_5190
Hypothetical protein.
  
 0.972
ftsZ
Cell division protein ftsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
  
 
 0.887
ftsW
Bacterial cell division membrane protein; Belongs to the SEDS family.
 
  
 0.846
iap
Cell wall-associated hydrolases (invasion-associated proteins).
 
 
 0.812
ACPL_2838
Hypothetical protein.
   
 
 0.796
ACPL_7707
Hypothetical protein.
   
 
 0.796
ftsI
Cell division protein FtsI/penicillin-binding protein 2.
 
  
 0.793
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.