STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_1083DNA-directed RNA polymerase II subunit RPB1; Fe-S oxidoreductase. (219 aa)    
Predicted Functional Partners:
smpB
SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...]
       0.565
ACPL_1418
Putative O-acetyltransferase; Predicted acyltransferases.
  
  
 0.554
ACPL_5135
Acyltransferase 3.
  
  
 0.554
ACPL_4099
Cellulase; Endoglucanase.
  
 
 0.509
celA
Endoglucanase.
  
 
 0.509
ACPL_3444
Putative mannan synthase 9; Glycosyltransferases, probably involved in cell wall biogenesis.
  
  
 0.465
ACPL_3447
N-acetylglucosaminyltransferase; Glycosyltransferases, probably involved in cell wall biogenesis.
  
  
 0.465
ACPL_7803
Putative xyloglucan glycosyltransferase 9; Glycosyltransferases, probably involved in cell wall biogenesis.
  
  
 0.465
pdc2
Pyruvate decarboxylase isozyme 2; Membrane proteins related to metalloendopeptidases.
  
    0.451
ACPL_8155
UDP-N-acetylglucosamine 2-epimerase; Belongs to the UDP-N-acetylglucosamine 2-epimerase family.
  
  
 0.422
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.