STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mtaP5'-methylthioadenosine phosphorylase; Purine nucleoside phosphorylase involved in purine salvage. (268 aa)    
Predicted Functional Partners:
mtnA
Methylthioribose-1-phosphate isomerase; Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family; Belongs to the eIF-2B alpha/beta/delta subunits family.
 
 
 0.986
apt-2
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
 
 0.894
ACPL_2395
Hypothetical protein.
 
  
 0.773
guaA
GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP.
  
 
 0.748
ACPL_4710
UDP-glucose 4-epimerase; Nucleoside-diphosphate-sugar epimerases.
 
   
 0.713
ACPL_4708
Uncharacterized protein conserved in bacteria.
 
   
 0.701
ACPL_4709
Glycosyltransferases involved in cell wall biogenesis.
 
   
 0.694
ACPL_4711
Hypothetical protein.
     
 0.600
ACPL_1118
Putative transcriptional regulator; Belongs to the UPF0301 (AlgH) family.
       0.571
add3
Adenosine deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
  
 
 0.510
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.