Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_1122Hypothetical protein. (193 aa)    
Predicted Functional Partners:
ACPL_1123
Hypothetical protein.
  
 
 0.986
ACPL_1124
Chaperone protein dnaK; Molecular chaperone.
  
 
 0.947
tapC
Type IV pilus assembly protein tapC; Type II secretory pathway, component PulF.
   
 
 0.798
pulE
General secretion pathway protein E; Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB.
  
 
 0.773
hofD
Leader peptidase (prepilin peptidase) / N-methyltransferase; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.
     
 0.722
pilT
Twitching motility protein; Tfp pilus assembly protein, pilus retraction ATPase PilT.
  
  
 0.657
gltB
Glutamate synthase domain 2.
       0.576
ACPL_1391
ComE operon protein 3; Predicted membrane metal-binding protein.
      
 0.568
fimA
Fimbrial protein; Type II secretory pathway, pseudopilin PulG.
  
  
 0.547
ACPL_2216
Uncharacterized protein containing LysM domain.
  
   0.482
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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