Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_1124Chaperone protein dnaK; Molecular chaperone. (340 aa)    
Predicted Functional Partners:
ACPL_1123
Hypothetical protein.
  
 
 0.983
tapC
Type IV pilus assembly protein tapC; Type II secretory pathway, component PulF.
 
 
 
 0.954
ACPL_1122
Hypothetical protein.
  
 
 0.947
pulE
General secretion pathway protein E; Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB.
 
 
 0.945
hofD
Leader peptidase (prepilin peptidase) / N-methyltransferase; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.
 
  
 0.933
pilT
Twitching motility protein; Tfp pilus assembly protein, pilus retraction ATPase PilT.
 
   
 0.905
fimA
Fimbrial protein; Type II secretory pathway, pseudopilin PulG.
 
  
 0.894
ACPL_1391
ComE operon protein 3; Predicted membrane metal-binding protein.
  
   
 0.644
pclO-2
Protein piccolo; Type V secretory pathway, adhesin AidA.
  
     0.626
ACPL_3427
Two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR; Osmosensitive K+ channel histidine kinase.
 
   
 0.583
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
Server load: low (28%) [HD]