STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fimAFimbrial protein; Type II secretory pathway, pseudopilin PulG. (168 aa)    
Predicted Functional Partners:
tapC
Type IV pilus assembly protein tapC; Type II secretory pathway, component PulF.
 
  
 0.969
pulE
General secretion pathway protein E; Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB.
 
 
 0.961
hofD
Leader peptidase (prepilin peptidase) / N-methyltransferase; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.
 
  
 0.921
pilT
Twitching motility protein; Tfp pilus assembly protein, pilus retraction ATPase PilT.
 
   
 0.915
ACPL_825
Hypothetical protein.
     
  0.900
ACPL_1124
Chaperone protein dnaK; Molecular chaperone.
 
  
 0.897
ACPL_1391
ComE operon protein 3; Predicted membrane metal-binding protein.
  
  
 0.663
ACPL_8325
Type 4 prepilin-like proteins leader peptide-processing enzyme; Type II secretory pathway, prepilin signal peptidase PulO and related peptidases.
 
  
 0.586
ACPL_7930
Hypothetical protein.
  
     0.574
ACPL_1122
Hypothetical protein.
  
  
 0.570
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
Server load: low (40%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.