Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ACPL_1133Nephrocystin-3; FOG: TPR repeat. (806 aa)    
Predicted Functional Partners:
ACPL_1135
Hypothetical protein.
 
     0.735
ACPL_3980
Putative WD repeat-containing protein; FOG: WD40 repeat.
 
 0.676
ACPL_6712
Serine/threonine protein kinase.
  
 
  0.672
dnaK-3
Molecular chaperone.
  
 0.618
ACPL_4783
Nephrocystin-3; FOG: TPR repeat.
  
 
 
0.604
ACPL_4883
Putative disease resistance protein RDL5/RF45; Predicted ATPase.
  
 
 
0.599
alaS
alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
   
 0.575
ACPL_1132
Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); Belongs to the anti-sigma-factor antagonist family.
  
    0.563
ogt-2
UDP-N-acetylglucosamine-peptide N-acetylglucosaminyltransferase 110 kDa subunit; FOG: TPR repeat.
   
 0.546
htpG
Chaperone protein htpG; Molecular chaperone, HSP90 family.
   
 0.543
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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