Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
adhCZn-dependent alcohol dehydrogenases, class III. (361 aa)    
Predicted Functional Partners:
ACPL_1151
yetL-like uncharacterized HTH-type transcriptional regulator; Transcriptional regulators.
 
     0.792
tcbF
Lactaldehyde reductase; Alcohol dehydrogenase, class IV.
    
 
 0.787
estA-4
Predicted esterase.
 
 
 0.783
ACPL_3309
Endo-1,4-beta-xylanase Z; Predicted esterase.
  
 
 0.750
ACPL_6769
Uncharacterized protein; Predicted esterase.
  
 
 0.750
tdh
L-threonine 3-dehydrogenase; Threonine dehydrogenase and related Zn-dependent dehydrogenases.
  
  
 0.743
ACPL_5197
Beta-lactamase domain protein; Zn-dependent hydrolases, including glyoxylases.
 
  
 0.737
ACPL_711
Copper-sensing transcriptional repressor csoR; Uncharacterized protein conserved in bacteria.
  
  
 0.603
ACPL_2866
Hypothetical protein.
  
  
 0.577
ACPL_5205
Hypothetical protein.
  
  
 0.577
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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