STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
pncBNicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. (425 aa)    
Predicted Functional Partners:
pncA
Nicotinamidase/pyrazinamidase; Amidases related to nicotinamidase.
 
 0.999
nadC
Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family.
   
 0.977
nadR
Transcriptional regulator nadR; FAD synthase.
    
 0.975
nadD
Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
 
 
 0.973
ACPL_7186
Putative competence-damage inducible protein; Uncharacterized protein (competence- and mitomycin-induced); Belongs to the CinA family.
  
 
 0.939
nudC
NAD+ diphosphatase; NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding.
    
 0.916
nudC-2
NAD+ diphosphatase; NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding.
    
 0.916
deoD
Purine-nucleoside phosphorylase.
     
 0.916
ACPL_680
5'-nucleotidase; Predicted extracellular nuclease.
    
 0.907
ACPL_888
5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family.
    
 0.907
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.