Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
hutUUrocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate. (544 aa)    
Predicted Functional Partners:
hutH
Histidine ammonia-lyase.
 
 0.999
hutI
Imidazolonepropionase and related amidohydrolases.
 
 
 0.999
ACPL_1175
N-formimino-L-glutamate deiminase; Cytosine deaminase and related metal-dependent hydrolases.
 
  
 0.968
ACPL_1176
N-carbamoyl-L-amino-acid hydrolase; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases.
 
     0.889
gcvP
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
  
  
 0.810
ACPL_1178
Glucosamine-fructose-6-phosphate aminotransferase; Isomerizing; Transcriptional regulators.
       0.776
ACPL_1025
Protein tolB.
  
  
 0.686
ACPL_272
Imidazolonepropionase and related amidohydrolases.
  
  
 0.660
ACPL_3269
Hypothetical protein.
  
  
 0.660
ACPL_3296
Uncharacterized protein; Imidazolonepropionase and related amidohydrolases.
  
  
 0.660
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.