STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_1182S-adenosylmethionine decarboxylase proenzyme; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine. (141 aa)    
Predicted Functional Partners:
metK
S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
    
 0.930
ACPL_5787
Site-specific DNA methylase.
     
  0.900
ACPL_7586
Hypothetical protein; Spermidine synthase.
  
  
 0.895
ACPL_7056
Pecanex-like protein 1; Transcription elongation factor.
  
     0.681
ACPL_770
Hypothetical protein.
  
     0.668
ACPL_3240
Hypothetical protein; Hydrolases of the alpha/beta superfamily.
  
     0.647
ACPL_7920
Flagellar motor switch/type III secretory pathway protein.
   
    0.639
bcp
Peroxiredoxin.
       0.625
ACPL_1286
Hypothetical protein.
  
     0.622
ACPL_6791
Endonuclease/exonuclease/phosphatase; Exonuclease III.
  
     0.616
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.