Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACPL_1237Putative signaling protein; MHYT domain (predicted integral membrane sensor domain). (288 aa)    
Predicted Functional Partners:
ACPL_3421
Osmosensitive K+ channel histidine kinase.
  
  
 0.518
ACPL_8227
Signal transduction histidine kinase.
  
  
 0.518
ACPL_4800
Two-component system, cell cycle sensor kinase and response regulator; Signal transduction histidine kinase.
 
    0.506
ACPL_2318
Signal transduction histidine kinase.
 
    0.497
ACPL_7815
Hypothetical protein.
   
    0.468
ACPL_1236
Chemotaxis response regulator protein-glutamate methylesterase; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
  
    0.441
phy1-5
Signal transduction histidine kinase.
 
  
 0.423
ACPL_700
Signal transduction histidine kinase.
  
    0.413
ACPL_4727
Signal transduction histidine kinase.
 
    0.406
hoxX
HoxX-like protein; Enoyl-CoA hydratase/carnithine racemase.
 
     0.405
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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