Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_1246Hypothetical protein. (255 aa)    
Predicted Functional Partners:
ACPL_1247
Putative secreted protein.
 
     0.949
ACPL_6712
Serine/threonine protein kinase.
  
     0.647
ACPL_2729
Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); Belongs to the anti-sigma-factor antagonist family.
  
     0.595
ACPL_1245
Hypothetical protein.
       0.588
ACPL_4317
Hypothetical protein; Predicted HD-superfamily hydrolase.
  
     0.551
ACPL_6713
Hypothetical protein.
  
     0.526
ACPL_2232
Parallel beta-helix repeat protein.
  
     0.489
ACPL_1250
Hypothetical protein.
 
     0.483
ACPL_699
Chemotaxis response regulator protein-glutamate methylesterase of group 3 operon; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains.
  
     0.481
ACPL_2231
Activated CDC42 kinase 1; FOG: PKD repeat.
  
     0.472
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.