Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
xylAXylose isomerase; Belongs to the xylose isomerase family. (394 aa)    
Predicted Functional Partners:
xylB-2
Xylulokinase; Glycerol kinase.
 
 
 0.998
xylB
Xylulokinase; Glycerol kinase.
  
 
 0.954
xyoA
FAD linked oxidase domain protein; FAD/FMN-containing dehydrogenases.
 
  
  0.922
frk2
Fructokinase; Sugar kinases, ribokinase family.
    
 0.907
pfkB
Fructokinase; Sugar kinases, ribokinase family.
    
 0.907
ACPL_6369
Threonine dehydrogenase and related Zn-dependent dehydrogenases.
     
 0.906
ACPL_3008
Beta-xylosidase; Belongs to the glycosyl hydrolase 43 family.
  
 
 0.849
abfA
alpha-N-arabinofuranosidase; Alpha-L-arabinofuranosidase.
 
  
 0.845
ACPL_1674
Glucokinase; Transcriptional regulator/sugar kinase.
    
 0.814
glcK
ROK family protein; Transcriptional regulator/sugar kinase.
    
 0.814
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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