Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_1263Hypothetical protein; Predicted phosphoesterases, related to the Icc protein. (250 aa)    
Predicted Functional Partners:
ACPL_1265
Hypothetical protein.
 
     0.968
ACPL_1264
Hypothetical protein.
       0.870
ACPL_1262
Hypothetical protein.
       0.749
ACPL_1266
Thymidylate kinase; ABC-type sugar transport systems, ATPase components.
 
     0.630
nadR
Transcriptional regulator nadR; FAD synthase.
       0.576
ACPL_5151
Hypothetical protein.
  
     0.504
ACPL_3707
Sensor histidine kinase/response regulator; FOG: HAMP domain.
  
     0.435
ACPL_260
Hypothetical protein.
  
     0.414
ACPL_398
GAF sensor hybrid histidine kinase; FOG: HAMP domain.
  
     0.407
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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