ssb protein (Actinoplanes sp. SE50110) - STRING interaction network

Nodes:

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Edges represent protein-protein associations

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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[Homology]

Score

ssb

Single-stranded DNA-binding protein. (215 aa)

Predicted Functional Partners:

ssb-2

0.917

ssb-3

0.915

rpsF

0.813

priA

0.786

rplU

0.750

holB

0.750

rplJ

0.732

topA

0.706

dnaE-2

0.704

rpsJ

0.703

Your Current Organism:

Actinoplanes sp. SE50110

NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
dnaE-2	holB	ACPL_1776	ACPL_496	DNA polymerase III, alpha subunit.	DNA polymerase III subunit delta; ATPase involved in DNA replication.	0.990
dnaE-2	ssb	ACPL_1776	ACPL_1290	DNA polymerase III, alpha subunit.	Single-stranded DNA-binding protein.	0.704
dnaE-2	ssb-2	ACPL_1776	ACPL_5803	DNA polymerase III, alpha subunit.	Single-stranded DNA-binding protein.	0.716
dnaE-2	ssb-3	ACPL_1776	ACPL_8344	DNA polymerase III, alpha subunit.	Single-stranded DNA-binding protein.	0.723
dnaE-2	topA	ACPL_1776	ACPL_490	DNA polymerase III, alpha subunit.	DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]	0.604
holB	dnaE-2	ACPL_496	ACPL_1776	DNA polymerase III subunit delta; ATPase involved in DNA replication.	DNA polymerase III, alpha subunit.	0.990
holB	priA	ACPL_496	ACPL_6465	DNA polymerase III subunit delta; ATPase involved in DNA replication.	Primosomal protein N' (replication factor Y) (superfamily II helicase); Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily.	0.574
holB	rplJ	ACPL_496	ACPL_771	DNA polymerase III subunit delta; ATPase involved in DNA replication.	50S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.	0.403
holB	ssb	ACPL_496	ACPL_1290	DNA polymerase III subunit delta; ATPase involved in DNA replication.	Single-stranded DNA-binding protein.	0.750
holB	ssb-2	ACPL_496	ACPL_5803	DNA polymerase III subunit delta; ATPase involved in DNA replication.	Single-stranded DNA-binding protein.	0.653
holB	ssb-3	ACPL_496	ACPL_8344	DNA polymerase III subunit delta; ATPase involved in DNA replication.	Single-stranded DNA-binding protein.	0.693
holB	topA	ACPL_496	ACPL_490	DNA polymerase III subunit delta; ATPase involved in DNA replication.	DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]	0.491
priA	holB	ACPL_6465	ACPL_496	Primosomal protein N' (replication factor Y) (superfamily II helicase); Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily.	DNA polymerase III subunit delta; ATPase involved in DNA replication.	0.574
priA	ssb	ACPL_6465	ACPL_1290	Primosomal protein N' (replication factor Y) (superfamily II helicase); Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily.	Single-stranded DNA-binding protein.	0.786
priA	ssb-2	ACPL_6465	ACPL_5803	Primosomal protein N' (replication factor Y) (superfamily II helicase); Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily.	Single-stranded DNA-binding protein.	0.803
priA	ssb-3	ACPL_6465	ACPL_8344	Primosomal protein N' (replication factor Y) (superfamily II helicase); Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily.	Single-stranded DNA-binding protein.	0.829
rplJ	holB	ACPL_771	ACPL_496	50S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.	DNA polymerase III subunit delta; ATPase involved in DNA replication.	0.403
rplJ	rplU	ACPL_771	ACPL_1376	50S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.	50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.	0.988
rplJ	rpsF	ACPL_771	ACPL_8345	50S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.	30S ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA.	0.989
rplJ	rpsJ	ACPL_771	ACPL_781	50S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.	30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.	0.990