STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_1294Peptidase M48 Ste24p; Zn-dependent protease with chaperone function. (359 aa)    
Predicted Functional Partners:
argE
Beta-Ala-His dipeptidase; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases.
     
 0.791
ACPL_1296
Monooxygenase, FAD-binding protein; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases.
       0.696
ACPL_1297
Hypothetical protein.
       0.636
cobQ
Adenosylcobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
  
    0.582
cobD
Adenosylcobinamide-phosphate synthase CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
       0.542
ACPL_4096
Hypothetical protein.
  
     0.498
grpE
Protein grpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]
 
  
 0.448
ACPL_1663
Phosphatidylinositol alpha-1, 6-mannosyltransferase; Glycosyltransferase.
  
 
   0.433
ACPL_7528
Endonuclease VIII; Formamidopyrimidine-DNA glycosylase.
     
 0.432
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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