node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACPL_519 | ku | ACPL_519 | ACPL_521 | DNA ligase (ATP); Predicted eukaryotic-type DNA primase. | DNA end-binding protein Ku; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family. | 0.966 |
ACPL_519 | ligB | ACPL_519 | ACPL_1298 | DNA ligase (ATP); Predicted eukaryotic-type DNA primase. | ATP-dependent DNA ligase. | 0.759 |
ACPL_519 | ligC-2 | ACPL_519 | ACPL_7071 | DNA ligase (ATP); Predicted eukaryotic-type DNA primase. | ATP-dependent DNA ligase. | 0.918 |
ACPL_7020 | ku | ACPL_7020 | ACPL_521 | DNA ligase (ATP); Predicted eukaryotic-type DNA primase. | DNA end-binding protein Ku; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family. | 0.897 |
ACPL_7020 | ligB | ACPL_7020 | ACPL_1298 | DNA ligase (ATP); Predicted eukaryotic-type DNA primase. | ATP-dependent DNA ligase. | 0.791 |
ACPL_7020 | ligC-2 | ACPL_7020 | ACPL_7071 | DNA ligase (ATP); Predicted eukaryotic-type DNA primase. | ATP-dependent DNA ligase. | 0.917 |
ACPL_7075 | ku | ACPL_7075 | ACPL_521 | DNA ligase (ATP); Predicted eukaryotic-type DNA primase. | DNA end-binding protein Ku; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family. | 0.897 |
ACPL_7075 | ligB | ACPL_7075 | ACPL_1298 | DNA ligase (ATP); Predicted eukaryotic-type DNA primase. | ATP-dependent DNA ligase. | 0.790 |
ACPL_7075 | ligC-2 | ACPL_7075 | ACPL_7071 | DNA ligase (ATP); Predicted eukaryotic-type DNA primase. | ATP-dependent DNA ligase. | 0.932 |
ACPL_7634 | dnaN | ACPL_7634 | ACPL_117 | DNA polymerase sliding clamp subunit (PCNA homolog). | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.433 |
ACPL_7634 | ligB | ACPL_7634 | ACPL_1298 | DNA polymerase sliding clamp subunit (PCNA homolog). | ATP-dependent DNA ligase. | 0.712 |
ACPL_7634 | ligC-2 | ACPL_7634 | ACPL_7071 | DNA polymerase sliding clamp subunit (PCNA homolog). | ATP-dependent DNA ligase. | 0.712 |
ACPL_7634 | polA | ACPL_7634 | ACPL_1827 | DNA polymerase sliding clamp subunit (PCNA homolog). | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.984 |
dnaN | ACPL_7634 | ACPL_117 | ACPL_7634 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA polymerase sliding clamp subunit (PCNA homolog). | 0.433 |
dnaN | ligB | ACPL_117 | ACPL_1298 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | ATP-dependent DNA ligase. | 0.712 |
dnaN | ligC-2 | ACPL_117 | ACPL_7071 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | ATP-dependent DNA ligase. | 0.712 |
dnaN | polA | ACPL_117 | ACPL_1827 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.990 |
ku | ACPL_519 | ACPL_521 | ACPL_519 | DNA end-binding protein Ku; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family. | DNA ligase (ATP); Predicted eukaryotic-type DNA primase. | 0.966 |
ku | ACPL_7020 | ACPL_521 | ACPL_7020 | DNA end-binding protein Ku; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family. | DNA ligase (ATP); Predicted eukaryotic-type DNA primase. | 0.897 |
ku | ACPL_7075 | ACPL_521 | ACPL_7075 | DNA end-binding protein Ku; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family. | DNA ligase (ATP); Predicted eukaryotic-type DNA primase. | 0.897 |