STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cobBCobyrinic acid a,c-diamide synthase. (799 aa)    
Predicted Functional Partners:
cobH
precorrin-8X methylmutase; Precorrin isomerase.
 
 
 0.989
btuR
ATP:corrinoid adenosyltransferase.
 
 
 0.984
cobN
Cobalamin biosynthesis protein CobN and related Mg-chelatases.
 
 
 0.982
cobI
Precorrin-2 C20-methyltransferase / precorrin-3B C17-methyltransferase; Precorrin-3B methylase.
 
  
 0.922
ACPL_7439
ATP-cobalamin adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family.
    
 0.914
cobM
Precorrin-4 methylase; Belongs to the precorrin methyltransferase family.
 
  
 0.908
cobB-2
Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.
  
  
 
0.904
cobL
precorrin-6Y C5,15-methyltransferase / precorrin-8W decarboxylase; Precorrin-6B methylase 1.
 
  
 0.895
cobE
Protein cobE; Cobalamin biosynthesis protein CbiG.
 
  
 0.890
cobC
Aspartate/tyrosine/aromatic aminotransferase.
  
 0.886
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.