Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_1310Hypothetical protein; Predicted thioesterase. (136 aa)    
Predicted Functional Partners:
ACPL_1311
Hypothetical protein.
  
    0.881
pks2A
Polyketide synthase modules and related proteins.
  
 
 0.868
pks3C
Polyketide synthase modules and related proteins.
  
 
 0.842
pks1E
Putative type-I PKS; Polyketide synthase modules and related proteins.
  
 
 0.824
pks1A
Polyketide synthase modules and related proteins.
  
 
 0.824
baeN
Thiotemplate mechanism natural product synthetase; Non-ribosomal peptide synthetase modules and related proteins.
  
 
 0.819
ACPL_1309
Putative ABC transporter ATP-binding protein; ATPase components of ABC transporters with duplicated ATPase domains.
       0.790
pks1B
Polyketide synthase modules and related proteins.
  
 
 0.724
pks3B
Polyketide synthase modules and related proteins.
  
 
 0.724
ACPL_7410
NAD-specific glutamate dehydrogenase.
 
    0.712
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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