STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_1316Small conductance mechanosensitive ion channel, MscS family; Small-conductance mechanosensitive channel. (333 aa)    
Predicted Functional Partners:
gcvP
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
   
    0.628
glbO
Truncated hemoglobins.
     
 0.595
mscL
Large-conductance mechanosensitive channel protein; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
     
 0.555
ACPL_868
Uncharacterized protein; Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta).
  
   
 0.516
ACPL_1317
Restriction endonuclease.
       0.494
ACPL_1315
yuxJ-like uncharacterized MFS-type transporter; Permeases of the major facilitator superfamily.
     
 0.487
ACPL_6566
Putative mscS family protein; Small-conductance mechanosensitive channel.
      
 0.470
ACPL_4809
Two-component system sensor protein; Signal transduction histidine kinase.
     
 0.443
ACPL_7633
Arginine exporter protein argO; Lysine efflux permease.
      
 0.422
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.