ACPL_133 protein (Actinoplanes sp. SE50110) - STRING interaction network

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ACPL_133

RNA pyrophosphohydrolase; ADP-ribose pyrophosphatase; Belongs to the Nudix hydrolase family. (136 aa)

Predicted Functional Partners:

gcvP

0.596

polA

0.550

ACPL_132

0.523

cobE

0.464

nrps1A

0.459

nrps1B

0.459

Your Current Organism:

Actinoplanes sp. SE50110

NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACPL_132	ACPL_133	ACPL_132	ACPL_133	Hypothetical protein.	RNA pyrophosphohydrolase; ADP-ribose pyrophosphatase; Belongs to the Nudix hydrolase family.	0.523
ACPL_133	ACPL_132	ACPL_133	ACPL_132	RNA pyrophosphohydrolase; ADP-ribose pyrophosphatase; Belongs to the Nudix hydrolase family.	Hypothetical protein.	0.523
ACPL_133	cobE	ACPL_133	ACPL_5301	RNA pyrophosphohydrolase; ADP-ribose pyrophosphatase; Belongs to the Nudix hydrolase family.	Protein cobE; Cobalamin biosynthesis protein CbiG.	0.464
ACPL_133	gcvP	ACPL_133	ACPL_4412	RNA pyrophosphohydrolase; ADP-ribose pyrophosphatase; Belongs to the Nudix hydrolase family.	Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.	0.596
ACPL_133	nrps1A	ACPL_133	ACPL_1013	RNA pyrophosphohydrolase; ADP-ribose pyrophosphatase; Belongs to the Nudix hydrolase family.	Amino acid adenylation domain-containing protein; Non-ribosomal peptide synthetase modules and related proteins.	0.459
ACPL_133	nrps1B	ACPL_133	ACPL_1014	RNA pyrophosphohydrolase; ADP-ribose pyrophosphatase; Belongs to the Nudix hydrolase family.	Non-ribosomal peptide synthetase modules and related proteins.	0.459
ACPL_133	polA	ACPL_133	ACPL_1827	RNA pyrophosphohydrolase; ADP-ribose pyrophosphatase; Belongs to the Nudix hydrolase family.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.550
cobE	ACPL_133	ACPL_5301	ACPL_133	Protein cobE; Cobalamin biosynthesis protein CbiG.	RNA pyrophosphohydrolase; ADP-ribose pyrophosphatase; Belongs to the Nudix hydrolase family.	0.464
gcvP	ACPL_133	ACPL_4412	ACPL_133	Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.	RNA pyrophosphohydrolase; ADP-ribose pyrophosphatase; Belongs to the Nudix hydrolase family.	0.596
gcvP	nrps1A	ACPL_4412	ACPL_1013	Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.	Amino acid adenylation domain-containing protein; Non-ribosomal peptide synthetase modules and related proteins.	0.432
gcvP	nrps1B	ACPL_4412	ACPL_1014	Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.	Non-ribosomal peptide synthetase modules and related proteins.	0.432
gcvP	polA	ACPL_4412	ACPL_1827	Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.477
nrps1A	ACPL_133	ACPL_1013	ACPL_133	Amino acid adenylation domain-containing protein; Non-ribosomal peptide synthetase modules and related proteins.	RNA pyrophosphohydrolase; ADP-ribose pyrophosphatase; Belongs to the Nudix hydrolase family.	0.459
nrps1A	gcvP	ACPL_1013	ACPL_4412	Amino acid adenylation domain-containing protein; Non-ribosomal peptide synthetase modules and related proteins.	Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.	0.432
nrps1A	nrps1B	ACPL_1013	ACPL_1014	Amino acid adenylation domain-containing protein; Non-ribosomal peptide synthetase modules and related proteins.	Non-ribosomal peptide synthetase modules and related proteins.	0.999
nrps1A	polA	ACPL_1013	ACPL_1827	Amino acid adenylation domain-containing protein; Non-ribosomal peptide synthetase modules and related proteins.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.615
nrps1B	ACPL_133	ACPL_1014	ACPL_133	Non-ribosomal peptide synthetase modules and related proteins.	RNA pyrophosphohydrolase; ADP-ribose pyrophosphatase; Belongs to the Nudix hydrolase family.	0.459
nrps1B	gcvP	ACPL_1014	ACPL_4412	Non-ribosomal peptide synthetase modules and related proteins.	Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.	0.432
nrps1B	nrps1A	ACPL_1014	ACPL_1013	Non-ribosomal peptide synthetase modules and related proteins.	Amino acid adenylation domain-containing protein; Non-ribosomal peptide synthetase modules and related proteins.	0.999
nrps1B	polA	ACPL_1014	ACPL_1827	Non-ribosomal peptide synthetase modules and related proteins.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.615

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