STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fdhAGlutathione-independent formaldehyde dehydrogenase; Threonine dehydrogenase and related Zn-dependent dehydrogenases. (386 aa)    
Predicted Functional Partners:
hybA
Formate dehydrogenase, beta subunit; Fe-S-cluster-containing hydrogenase components 1.
     
 0.903
ACPL_5754
Formate dehydrogenase, alpha subunit; Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
     
 0.903
ACPL_5755
Formate dehydrogenase, alpha subunit; Uncharacterized anaerobic dehydrogenase.
     
  0.900
pfpI-2
Intracellular protease 1.
 
    0.775
pfpI
Putative intracellular protease/amidase.
  
    0.774
ACPL_1344
Putative 17.2 kDa protein in melC2-rnhH intergenic region; Predicted integral membrane protein.
 
    0.743
tdh
L-threonine 3-dehydrogenase; Threonine dehydrogenase and related Zn-dependent dehydrogenases.
  
     0.685
fdh
Threonine dehydrogenase and related Zn-dependent dehydrogenases.
 
    
0.588
ACPL_7029
Polyketide synthase modules and related proteins.
  
  
 0.433
bioF
8-amino-7-oxononanoate synthase; 7-keto-8-aminopelargonate synthetase and related enzymes.
  
  
 0.402
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
Server load: medium (46%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.