Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
fdhAGlutathione-independent formaldehyde dehydrogenase; Threonine dehydrogenase and related Zn-dependent dehydrogenases. (386 aa)    
Predicted Functional Partners:
hybA
Formate dehydrogenase, beta subunit; Fe-S-cluster-containing hydrogenase components 1.
     
 0.902
ACPL_5754
Formate dehydrogenase, alpha subunit; Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
     
 0.902
ACPL_5755
Formate dehydrogenase, alpha subunit; Uncharacterized anaerobic dehydrogenase.
     
 0.900
pfpI-2
Intracellular protease 1.
 
    0.775
pfpI
Putative intracellular protease/amidase.
  
    0.773
ACPL_1344
Putative 17.2 kDa protein in melC2-rnhH intergenic region; Predicted integral membrane protein.
 
    0.742
tdh
L-threonine 3-dehydrogenase; Threonine dehydrogenase and related Zn-dependent dehydrogenases.
  
     0.685
fdh
Threonine dehydrogenase and related Zn-dependent dehydrogenases.
 
    
0.587
ACPL_5250
tRNA (adenine-N1-)-methyltransferase; Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
     
  0.426
trmB
tRNA (guanine-N7-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
     
  0.426
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.