STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_1370Multi-sensor signal transduction histidine kinase; Serine phosphatase RsbU, regulator of sigma subunit. (832 aa)    
Predicted Functional Partners:
ACPL_1371
Hypothetical protein.
  
   0.869
rsbV
Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); Belongs to the anti-sigma-factor antagonist family.
 
   0.797
rsbV-2
Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); Belongs to the anti-sigma-factor antagonist family.
 
   0.790
ACPL_4095
Serine phosphatase RsbU, regulator of sigma subunit.
  
     0.769
ACPL_1369
Carboxylesterase bioH; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).
 
    0.750
ACPL_302
Protein icfG; Serine phosphatase RsbU, regulator of sigma subunit.
  
     0.745
ACPL_1372
Radical SAM domain protein; Fe-S oxidoreductase.
       0.697
rsbV-3
Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); Belongs to the anti-sigma-factor antagonist family.
 
   0.662
rsbW
Serine-protein kinase rsbW; Anti-sigma regulatory factor (Ser/Thr protein kinase).
  
   0.650
ACPL_2318
Signal transduction histidine kinase.
  
 0.644
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.