Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACPL_1370Multi-sensor signal transduction histidine kinase; Serine phosphatase RsbU, regulator of sigma subunit. (832 aa)    
Predicted Functional Partners:
ACPL_1371
Hypothetical protein.
  
   0.861
rsbV
Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); Belongs to the anti-sigma-factor antagonist family.
 
   0.788
rsbV-2
Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); Belongs to the anti-sigma-factor antagonist family.
 
   0.781
ACPL_4095
Serine phosphatase RsbU, regulator of sigma subunit.
  
     0.769
ACPL_1369
Carboxylesterase bioH; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).
 
    0.749
ACPL_302
Protein icfG; Serine phosphatase RsbU, regulator of sigma subunit.
  
     0.745
ACPL_1372
Radical SAM domain protein; Fe-S oxidoreductase.
       0.697
ACPL_2318
Signal transduction histidine kinase.
 
  
 0.662
rsbV-3
Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); Belongs to the anti-sigma-factor antagonist family.
 
   0.647
rsbW
Serine-protein kinase rsbW; Anti-sigma regulatory factor (Ser/Thr protein kinase).
  
   0.645
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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