Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACPL_1373Uncharacterized protein conserved in bacteria. (244 aa)    
Predicted Functional Partners:
ACPL_1372
Radical SAM domain protein; Fe-S oxidoreductase.
 
    0.946
ACPL_7546
Hypothetical protein.
  
     0.746
ACPL_1374
Ribonucleases G and E.
       0.608
ACPL_1370
Multi-sensor signal transduction histidine kinase; Serine phosphatase RsbU, regulator of sigma subunit.
       0.563
ACPL_1371
Hypothetical protein.
       0.551
ACPL_1369
Carboxylesterase bioH; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).
       0.487
obgE
GTPase ObgE; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
  
    0.422
rplU
50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
       0.419
rpmA
Ribosomal protein L27; Belongs to the bacterial ribosomal protein bL27 family.
       0.419
ACPL_1659
DNA polymerase III subunit epsilon; Nuclease subunit of the excinuclease complex.
   
    0.412
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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