STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_138Inosine-5'-monophosphate dehydrogenase; FOG: CBS domain. (129 aa)    
Predicted Functional Partners:
ACPL_4157
Hypothetical protein.
   
  
 0.851
ACPL_4154
Hypothetical protein; Nitroreductase.
   
  
 0.808
ACPL_2034
Hypothetical protein.
   
  
 0.804
ACPL_4003
Hypothetical protein.
   
  
 0.804
guaA
GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP.
 
  
 0.792
ACPL_5251
Peptidase M50; Zn-dependent proteases; Belongs to the peptidase M50B family.
  
    0.782
ACPL_1513
PfkB domain protein; Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB).
   
    0.636
ACPL_6373
Phosphofructokinase; Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB); Belongs to the carbohydrate kinase PfkB family.
   
    0.636
ACPL_1569
GMP synthase; Glutamine-hydrolyzing; GMP synthase - Glutamine amidotransferase domain.
    
 0.565
hspX
Molecular chaperone (small heat shock protein); Belongs to the small heat shock protein (HSP20) family.
 
  
 0.516
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
Server load: low (32%) [HD]