Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_138Inosine-5'-monophosphate dehydrogenase; FOG: CBS domain. (129 aa)    
Predicted Functional Partners:
ACPL_4157
Hypothetical protein.
   
  
 0.848
ACPL_2034
Hypothetical protein.
   
  
 0.802
ACPL_4003
Hypothetical protein.
   
  
 0.802
ACPL_4154
Hypothetical protein; Nitroreductase.
   
  
 0.796
ACPL_5251
Peptidase M50; Zn-dependent proteases; Belongs to the peptidase M50B family.
  
    0.778
guaA
GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP.
 
  
 0.778
gltB
Glutamate synthase domain 2.
     
 0.627
ACPL_1513
PfkB domain protein; Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB).
   
  
 0.579
ACPL_6373
Phosphofructokinase; Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB); Belongs to the carbohydrate kinase PfkB family.
   
  
 0.579
ACPL_1569
GMP synthase; Glutamine-hydrolyzing; GMP synthase - Glutamine amidotransferase domain.
    
 0.562
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
Server load: low (14%) [HD]