Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ACPL_1390ComE operon protein 1; Transcriptional accessory protein. (282 aa)    
Predicted Functional Partners:
ACPL_1391
ComE operon protein 3; Predicted membrane metal-binding protein.
 
  
 0.890
ACPL_1330
Uncharacterized protein; Predicted acetyltransferase involved in intracellular survival and related acetyltransferases.
  
    0.682
tapC
Type IV pilus assembly protein tapC; Type II secretory pathway, component PulF.
  
  
 0.640
ACPL_5319
Membrane-bound protein lytR; Transcriptional regulator.
 
     0.637
pulE
General secretion pathway protein E; Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB.
  
  
 0.631
ACPL_2049
Cell envelope-related transcriptional attenuator; Transcriptional regulator.
 
     0.620
ACPL_1393
Collagen alpha-5(VI) chain; PPE-repeat proteins.
 
     0.575
ACPL_7592
Membrane-bound protein lytR; Transcriptional regulator.
 
     0.564
ACPL_1392
DNA polymerase III, delta subunit.
     
 0.534
hofD
Leader peptidase (prepilin peptidase) / N-methyltransferase; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.
   
  
 0.531
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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