Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_1399yeaQ-like uncharacterized protein. (91 aa)    
Predicted Functional Partners:
ACPL_2677
Ymge-like uncharacterized protein.
  
     0.577
lepA
GTP-binding protein lepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.
       0.560
egtD
Uncharacterized protein; Catalyzes the SAM-dependent triple methylation of the alpha- amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine; Belongs to the methyltransferase superfamily. EgtD family.
   
    0.503
ACPL_2384
Sporulation-control protein spo0M; Sporulation control protein.
  
     0.495
ACPL_3895
Putative anti-sigma regulatory factor, serine/threonine protein kinase.
  
    0.472
ACPL_1906
Cu/Zn superoxide dismutase.
  
    0.461
prsR-3
Anti-sigma F factor; Signal transduction histidine kinase.
  
    0.458
ACPL_3248
Anti-sigma regulatory factor (Ser/Thr protein kinase).
  
    0.450
ACPL_3517
Anti-sigma F factor; FOG: PAS/PAC domain.
  
    0.440
ACPL_7138
Sporulation-control protein spo0M; Sporulation control protein.
  
     0.434
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.