htpG protein (Actinoplanes sp. SE50110) - STRING interaction network

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htpG

Chaperone protein htpG; Molecular chaperone, HSP90 family. (602 aa)

Predicted Functional Partners:

ACPL_142

0.971

htpG-2

0.922

groL

0.898

groL-2

0.898

aap

0.884

dnaJ

0.868

dnaJ-2

0.868

dnaK-4

0.850

dnaK-3

0.846

ACPL_4783

0.842

Your Current Organism:

Actinoplanes sp. SE50110

NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACPL_142	dnaK-3	ACPL_142	ACPL_3423	Hypothetical protein; FOG: TPR repeat.	Molecular chaperone.	0.599
ACPL_142	dnaK-4	ACPL_142	ACPL_8203	Hypothetical protein; FOG: TPR repeat.	Heat shock protein 70; Molecular chaperone; Belongs to the heat shock protein 70 family.	0.607
ACPL_142	htpG	ACPL_142	ACPL_141	Hypothetical protein; FOG: TPR repeat.	Chaperone protein htpG; Molecular chaperone, HSP90 family.	0.971
ACPL_4783	aap	ACPL_4783	ACPL_2338	Nephrocystin-3; FOG: TPR repeat.	Collagen alpha-4(VI) chain; Uncharacterized protein containing caspase domain.	0.836
ACPL_4783	dnaK-3	ACPL_4783	ACPL_3423	Nephrocystin-3; FOG: TPR repeat.	Molecular chaperone.	0.834
ACPL_4783	dnaK-4	ACPL_4783	ACPL_8203	Nephrocystin-3; FOG: TPR repeat.	Heat shock protein 70; Molecular chaperone; Belongs to the heat shock protein 70 family.	0.765
ACPL_4783	groL	ACPL_4783	ACPL_7986	Nephrocystin-3; FOG: TPR repeat.	60 kDa chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.	0.788
ACPL_4783	groL-2	ACPL_4783	ACPL_854	Nephrocystin-3; FOG: TPR repeat.	60 kDa chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.	0.788
ACPL_4783	htpG	ACPL_4783	ACPL_141	Nephrocystin-3; FOG: TPR repeat.	Chaperone protein htpG; Molecular chaperone, HSP90 family.	0.842
ACPL_4783	htpG-2	ACPL_4783	ACPL_3056	Nephrocystin-3; FOG: TPR repeat.	Chaperone protein htpG; Molecular chaperone. Has ATPase activity.	0.842
aap	ACPL_4783	ACPL_2338	ACPL_4783	Collagen alpha-4(VI) chain; Uncharacterized protein containing caspase domain.	Nephrocystin-3; FOG: TPR repeat.	0.836
aap	dnaJ	ACPL_2338	ACPL_1406	Collagen alpha-4(VI) chain; Uncharacterized protein containing caspase domain.	Chaperone protein dnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]	0.789
aap	dnaJ-2	ACPL_2338	ACPL_202	Collagen alpha-4(VI) chain; Uncharacterized protein containing caspase domain.	Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...]	0.789
aap	dnaK-3	ACPL_2338	ACPL_3423	Collagen alpha-4(VI) chain; Uncharacterized protein containing caspase domain.	Molecular chaperone.	0.858
aap	dnaK-4	ACPL_2338	ACPL_8203	Collagen alpha-4(VI) chain; Uncharacterized protein containing caspase domain.	Heat shock protein 70; Molecular chaperone; Belongs to the heat shock protein 70 family.	0.795
aap	htpG	ACPL_2338	ACPL_141	Collagen alpha-4(VI) chain; Uncharacterized protein containing caspase domain.	Chaperone protein htpG; Molecular chaperone, HSP90 family.	0.884
aap	htpG-2	ACPL_2338	ACPL_3056	Collagen alpha-4(VI) chain; Uncharacterized protein containing caspase domain.	Chaperone protein htpG; Molecular chaperone. Has ATPase activity.	0.884
dnaJ	aap	ACPL_1406	ACPL_2338	Chaperone protein dnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]	Collagen alpha-4(VI) chain; Uncharacterized protein containing caspase domain.	0.789
dnaJ	dnaK-3	ACPL_1406	ACPL_3423	Chaperone protein dnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]	Molecular chaperone.	0.955
dnaJ	dnaK-4	ACPL_1406	ACPL_8203	Chaperone protein dnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]	Heat shock protein 70; Molecular chaperone; Belongs to the heat shock protein 70 family.	0.945