htpG protein (Actinoplanes sp. SE50110) - STRING interaction network

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Predicted Interactions

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Score

htpG

Chaperone protein htpG; Molecular chaperone, HSP90 family. (602 aa)

Predicted Functional Partners:

ACPL_142

0.979

ACPL_8205

0.908

ACPL_3161

0.884

ACPL_6712

0.884

dnaJ

0.845

dnaJ-2

0.845

groL

0.823

groL-2

0.823

dnaK-4

0.818

groS

0.815

Your Current Organism:

Actinoplanes sp. SE50110

NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACPL_142	ACPL_8205	ACPL_142	ACPL_8205	Hypothetical protein; FOG: TPR repeat.	Hypothetical protein.	0.690
ACPL_142	htpG	ACPL_142	ACPL_141	Hypothetical protein; FOG: TPR repeat.	Chaperone protein htpG; Molecular chaperone, HSP90 family.	0.979
ACPL_3161	ACPL_8205	ACPL_3161	ACPL_8205	Hypothetical protein.	Hypothetical protein.	0.971
ACPL_3161	htpG	ACPL_3161	ACPL_141	Hypothetical protein.	Chaperone protein htpG; Molecular chaperone, HSP90 family.	0.884
ACPL_6712	ACPL_8205	ACPL_6712	ACPL_8205	Serine/threonine protein kinase.	Hypothetical protein.	0.974
ACPL_6712	htpG	ACPL_6712	ACPL_141	Serine/threonine protein kinase.	Chaperone protein htpG; Molecular chaperone, HSP90 family.	0.884
ACPL_8205	ACPL_142	ACPL_8205	ACPL_142	Hypothetical protein.	Hypothetical protein; FOG: TPR repeat.	0.690
ACPL_8205	ACPL_3161	ACPL_8205	ACPL_3161	Hypothetical protein.	Hypothetical protein.	0.971
ACPL_8205	ACPL_6712	ACPL_8205	ACPL_6712	Hypothetical protein.	Serine/threonine protein kinase.	0.974
ACPL_8205	dnaJ	ACPL_8205	ACPL_1406	Hypothetical protein.	Chaperone protein dnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]	0.643
ACPL_8205	dnaJ-2	ACPL_8205	ACPL_202	Hypothetical protein.	Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...]	0.643
ACPL_8205	dnaK-4	ACPL_8205	ACPL_8203	Hypothetical protein.	Heat shock protein 70; Molecular chaperone; Belongs to the heat shock protein 70 family.	0.917
ACPL_8205	groL	ACPL_8205	ACPL_7986	Hypothetical protein.	60 kDa chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.	0.453
ACPL_8205	groL-2	ACPL_8205	ACPL_854	Hypothetical protein.	60 kDa chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.	0.453
ACPL_8205	htpG	ACPL_8205	ACPL_141	Hypothetical protein.	Chaperone protein htpG; Molecular chaperone, HSP90 family.	0.908
dnaJ	ACPL_8205	ACPL_1406	ACPL_8205	Chaperone protein dnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]	Hypothetical protein.	0.643
dnaJ	dnaK-4	ACPL_1406	ACPL_8203	Chaperone protein dnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]	Heat shock protein 70; Molecular chaperone; Belongs to the heat shock protein 70 family.	0.933
dnaJ	groL	ACPL_1406	ACPL_7986	Chaperone protein dnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]	60 kDa chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.	0.809
dnaJ	groL-2	ACPL_1406	ACPL_854	Chaperone protein dnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]	60 kDa chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.	0.808
dnaJ	groS	ACPL_1406	ACPL_855	Chaperone protein dnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]	10 kDa chaperonin; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.	0.739