STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_1425Hypothetical protein. (305 aa)    
Predicted Functional Partners:
metH
5-methyltetrahydrofolate-homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
  
 0.972
ACPL_7391
Methionine synthase vitamin-B12 independent.
  
 
 0.868
gltB
Glutamate synthase domain 2.
  
  
 0.716
metK
S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
  
  
 0.715
mtnA
Methylthioribose-1-phosphate isomerase; Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family; Belongs to the eIF-2B alpha/beta/delta subunits family.
  
  
 0.685
megL
Methionine-gamma-lyase; Cystathionine beta-lyases/cystathionine gamma-synthases.
  
 
 0.655
ACPL_1424
Uncharacterized protein.
       0.655
cysA
Cystathionine beta-lyases/cystathionine gamma-synthases.
  
 
 0.655
metB
Cystathionine beta-lyases/cystathionine gamma-synthases.
  
 
 0.655
ACPL_1423
Haloacid dehalogenase domain protein hydrolase; Predicted phosphatases.
       0.642
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.