Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_143Transcriptional regulator. (201 aa)    
Predicted Functional Partners:
ACPL_142
Hypothetical protein; FOG: TPR repeat.
       0.691
ACPL_139
Arylesterase; Lysophospholipase L1 and related esterases.
 
     0.683
htpG
Chaperone protein htpG; Molecular chaperone, HSP90 family.
       0.678
sseA
Rhodanese-related sulfurtransferase.
       0.634
yngH
Biotin carboxylase.
   
   0.579
mvaB
hydroxymethylglutaryl-CoA lyase; Isopropylmalate/homocitrate/citramalate synthases.
       0.563
ACPL_138
Inosine-5'-monophosphate dehydrogenase; FOG: CBS domain.
  
    0.404
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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