Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
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[Homology]
Score
cah4Carbonic anhydrase; Similar to chloroplast protein; Carbonic anhydrase. (200 aa)    
Predicted Functional Partners:
st2
Carbonic anhydrase; Sulfate permease and related transporters (MFS superfamily).
 
 
 0.982
ACPL_4101
Carbonic anhydrase; Similar to chloroplast protein; Carbonic anhydrase.
    
 0.938
apt
Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins.
   
    0.733
apt-2
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
   
    0.733
cysE-2
Acetyltransferase; Isoleucine patch superfamily.
    
 
 0.644
ACPL_1516
2-hydroxy-6-oxononadienedioate/2-hydroxy-6- oxononatrienedioate hydrolase 2; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).
 
     0.596
mutY
A/G-specific DNA glycosylase.
     
 0.432
gltB
Glutamate synthase domain 2.
  
  
 0.408
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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