STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_1548Sodium/glucose cotransporter 1; Na+/proline symporter. (547 aa)    
Predicted Functional Partners:
ACPL_1547
Hypothetical protein.
 
     0.955
putA
NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family.
  
  
 0.904
ACPL_7874
Proline dehydrogenase.
  
  
 0.697
ACPL_4809
Two-component system sensor protein; Signal transduction histidine kinase.
  
 
 0.655
lamA
Biotin carboxylase.
  
  
 0.649
apt
Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins.
   
  
 0.530
apt-2
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
   
  
 0.530
barA
Sensory box histidine kinase/response regulator; Signal transduction histidine kinase.
  
  
 0.517
pxpA
Uncharacterized protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
  
    0.504
etr2-2
Ethylene receptor 2; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
  
  
 0.491
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.