Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
tdcBThreonine dehydratase. (295 aa)    
Predicted Functional Partners:
ilvH
Acetolactate synthase, small (regulatory) subunit.
  
 0.953
ilvB
Acetolactate synthase 1 catalytic subunit; Thiamine pyrophosphate-requiring enzymes.
 
 0.950
leuB
Isocitrate/isopropylmalate dehydrogenase.
  
 0.946
ACPL_7475
Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine.
  
 
 0.939
sdaA
L-serine deaminase; Belongs to the iron-sulfur dependent L-serine dehydratase family.
  
 
 0.935
ACPL_7989
Threonine synthase.
  
 
 0.935
trpB
Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
  
 0.931
trpB-2
Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
  
 0.931
ilvA
Threonine dehydratase.
  
  
 
0.928
cysM-2
Cystathionine beta-synthase; Cysteine synthase.
 
 
 0.925
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.