Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACPL_1604ATPase family gene 2 protein; ATPases of the AAA+ class. (552 aa)    
Predicted Functional Partners:
acuC
Deacetylases, including yeast histone deacetylase and acetoin utilization protein.
 
 
 0.792
ACPL_1605
Translation initiation factor IF-2; PPE-repeat proteins.
       0.757
ACPL_1165
Mov34/MPN/PAD-1 family protein; Predicted metal-dependent protease of the PAD1/JAB1 superfamily.
   
 0.662
arc
Proteasome-associated ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.
   
  0.640
ACPL_1603
Otogelin.
     
 0.615
ACPL_3980
Putative WD repeat-containing protein; FOG: WD40 repeat.
   
 0.605
ACPL_8364
Putative WD repeat-containing protein; FOG: WD40 repeat.
   
 0.605
rplJ
50S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.
   
 0.599
ACPL_8205
Hypothetical protein.
    
 0.594
ACPL_1598
Hypothetical protein.
 
   
 0.587
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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