Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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ACPL_1656Nucleotidyl transferase; Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon). (313 aa)    
Predicted Functional Partners:
rmlC
dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes.
  
  
 0.845
mpg2
Nucleotidyl transferase; Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon).
 
  
 0.786
ACPL_1657
NTP pyrophosphohydrolases including oxidative damage repair enzymes.
 
     0.755
ugd
UDPglucose 6-dehydrogenase; UDP-N-acetyl-D-mannosaminuronate dehydrogenase.
  
  
 0.737
udgA
Predicted UDP-glucose 6-dehydrogenase.
  
  
 0.737
ACPL_353
NAD-dependent epimerase/dehydratase; dTDP-D-glucose 4,6-dehydratase.
 
  
 0.683
ACPL_1655
Leucine-responsive regulatory protein.
       0.675
rmlB
dTDP-D-glucose 4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.
  
  
 0.627
acbB
dTDP-glucose 4,6-dehydratase; Probably involved in the biosynthesis of the acarviose moiety of the alpha-glucosidase inhibitor acarbose. Catalyzes the dehydration of dTDP-D-glucose to form dTDP-6-deoxy-D- xylo-4-hexulose via a three-step process involving oxidation, dehydration and reduction (By similarity). Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.
  
  
 0.627
rmlD
dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.
  
  
 0.594
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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