STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_1657NTP pyrophosphohydrolases including oxidative damage repair enzymes. (187 aa)    
Predicted Functional Partners:
ACPL_1656
Nucleotidyl transferase; Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon).
 
    0.769
ACPL_1655
Leucine-responsive regulatory protein.
       0.679
relA
(p)ppGpp synthetase I, SpoT/RelA; Guanosine polyphosphate pyrophosphohydrolases/synthetases.
       0.673
ACPL_8108
Putative ATPase.
  
     0.670
ACPL_1511
Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); Belongs to the anti-sigma-factor antagonist family.
  
     0.614
ACPL_720
Protein Daple; Type V secretory pathway, adhesin AidA.
  
     0.596
ACPL_8273
Cholinephosphotransferase 1; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
 
     0.578
ACPL_7255
Protein piccolo.
  
     0.576
ACPL_562
Uncharacterized protein conserved in bacteria.
  
     0.560
ACPL_1659
DNA polymerase III subunit epsilon; Nuclease subunit of the excinuclease complex.
     
 0.557
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.