Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
whiPwhiP-like uncharacterized membrane protein; Involved in cell division; Belongs to the CrgA family. (87 aa)    
Predicted Functional Partners:
trpG
Anthranilate/para-aminobenzoate synthases component II.
       0.634
ACPL_168
Hypothetical protein.
       0.634
ACPL_169
yhcS-like uncharacterized protein; Polyketide synthase modules and related proteins.
       0.634
ACPL_170
Uncharacterized protein conserved in bacteria.
       0.634
ftsZ
Cell division protein ftsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
    
 
 0.628
ftsI
Cell division protein FtsI/penicillin-binding protein 2.
   
 
 0.614
ACPL_1767
YggT family protein; Predicted integral membrane protein.
  
     0.611
ACPL_161
Oxoglutarate dehydrogenase inhibitor; FOG: FHA domain.
 
  
 0.608
ftsW
Bacterial cell division membrane protein; Belongs to the SEDS family.
     
 0.601
pbpA
Peptidoglycan glycosyltransferase; Cell division protein FtsI/penicillin-binding protein 2.
   
 
 0.586
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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