Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
manRMandelate racemase; L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily; Belongs to the mandelate racemase/muconate lactonizing enzyme family. (358 aa)    
Predicted Functional Partners:
ACPL_1712
Beta-lactamase class C and other penicillin binding proteins.
  
  
 0.787
garD
Altronate dehydratase.
 
  
 0.605
kdgA
2-dehydro-3-deoxyphosphogluconate aldolase / 4-hydroxy-2-oxoglutarate aldolase; 2-keto-3-deoxy-6-phosphogluconate aldolase.
 
   
 0.517
apbA
2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
  
    0.498
ACPL_1711
Restriction endonuclease.
       0.480
uxaC
Glucuronate isomerase.
 
   
 0.459
ACPL_2757
Catechol 1,2-dioxygenase; Protocatechuate 3,4-dioxygenase beta subunit.
 
  
 0.447
uxuB
Fructuronate reductase; Mannitol-1-phosphate/altronate dehydrogenases.
 
   
 0.444
hpcE
5-oxopent-3-ene-1,2,5- tricarboxylatedecarboxylas E; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases).
 
   
 0.442
nagK
Predicted N-acetylglucosamine kinase.
 
    0.426
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.