Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
sti1Protease inhibitor SIL-V3; Belongs to the protease inhibitor I16 (SSI) family. (124 aa)    
Predicted Functional Partners:
aprA-2
Peptidase S8/S53 subtilisin kexin sedolisin; Subtilisin-like serine proteases; Belongs to the peptidase S8 family.
 
 0.681
ACPL_1739
Nucleotidyltransferase/DNA polymerase involved in DNA repair.
   
   0.665
ACPL_1742
Ubiquinone/menaquinone biosynthesis methyltransferase ubiE; SAM-dependent methyltransferases.
 
     0.663
dnaE
DNA polymerase III subunit alpha; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.
       0.640
ACPL_492
Transcriptional regulator, TetR family; Transcriptional regulator.
  
     0.636
ACPL_644
Hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection; Belongs to the YbaB/EbfC family.
  
    0.628
ACPL_1743
2,3-bisphosphoglycerate-independent phosphoglycerate mutase 2; Uncharacterized proteins of the AP superfamily.
       0.615
ACPL_5956
Predicted membrane-bound metal-dependent hydrolases.
  
     0.543
ACPL_6911
Collagen alpha-4(VI) chain; Secreted and surface protein containing fasciclin-like repeats.
  
 0.517
ACPL_1603
Otogelin.
  
 
   0.513
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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