Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACPL_17432,3-bisphosphoglycerate-independent phosphoglycerate mutase 2; Uncharacterized proteins of the AP superfamily. (438 aa)    
Predicted Functional Partners:
ACPL_1742
Ubiquinone/menaquinone biosynthesis methyltransferase ubiE; SAM-dependent methyltransferases.
       0.873
ACPL_1744
Hypothetical protein.
 
     0.626
sti1
Protease inhibitor SIL-V3; Belongs to the protease inhibitor I16 (SSI) family.
       0.615
dnaE
DNA polymerase III subunit alpha; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.
       0.566
ACPL_1739
Nucleotidyltransferase/DNA polymerase involved in DNA repair.
       0.520
ACPL_2615
Putative inorganic polyphosphate/ATP-NAD kinase; Predicted sugar kinase.
   
 
  0.506
ppnK
NAD+ kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
   
 
  0.506
nadK
NAD+ kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
   
 
  0.506
ACPL_2286
Hypothetical protein.
    
  0.443
yic1
Alpha-xylosidase; Alpha-glucosidases, family 31 of glycosyl hydrolases; Belongs to the glycosyl hydrolase 31 family.
    
  0.443
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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